PROTEINS OF KNOWN STRUCTURE BY SOLID-STATE NMR

The table below provides information about proteins whose structures have been determined by solid-state NMR, to a resolution sufficient to have resulted in a file deposited with the worldwide Protein Data Bank. It has been maintained on this page between 2008 and 2018.

The new database is now available on Antoine Loquet's Website:

Database of membrane protein structures solved by solution and solid-state NMR

Database of protein structures solved by solid-state NMR


Protein	PDB Entry	BMRB Entry	Oligomer Size/State	Production Source	Reconstitution Medium	NMR Method	PubMed Reference
ALIGNABLE SOLUBLE PROTEINS
fd coat protein in filamentous bacteriophage	1NH4	5815	5 kDa/1	Escherichia coli	-	oriented	Zeri et al. (2003)
Pf1 coat protein in filamentous bacteriophage (at various temperatures)	1PJF 1ZN5 2XKM	5877	5 kDa/1	Pseudomonas aeruginosa	-	oriented	Thiriot et al. (2004) Thiriot et al. (2004) Strauss et al. (2011)

MICRO-CRYSTALLINE SOLUBLE PROTEINS
Spectrin SH3 domain	1M8M		7 kDa/1	Escherichia coli	-	MAS	Castellani et al. (2002)
Kaliotoxin	1XSW	6351	4 kDa/1	Escherichia coli	-	MAS	Lange et al. (2005)
beta1 immunoglobulin binding domain of protein G (GB1)	2JU6 2JSV 2K0P 2KQ4 2KWD 2LGI	15156	6 kDa/1	Escherichia coli	-	MAS	Zhou et al. (2007) Franks et al. (2008) Robustelli et al. (2008) Nieuwkoop et al. (2009) Nieuwkoop and Rienstra (2010) Wylie et al. (2011)
Crh domain, swapped dimer	2RLZ	5757	19 kDa/2	Escherichia coli	-	MAS	Loquet et al. (2008)
Ubiquitin	2JZZ 2L3Z		9 kDa/1	Escherichia coli	-	MAS	Manolikas et al. (2008) Huber et al. (2011)
MMP-12 (Macrophage metalloelastase)	2K9C 2KRJ	7415	17 kDa/1	Escherichia coli	-	MAS	Balayssac et al. (2008) Bertini et al. (2010)
Cu(I),Zn(II) superoxide dismutase	2LU5	18509	16 kDa/1	Escherichia coli	-	MAS	Knight et al. (2012)
Cap-Gly domain of mammalian dynactin	2M02	17937	10 kDa/1	Escherichia coli	-	MAS	Yan et al. (2013)

PROTEINS FORMING FIBRILS
Transthyretin amyloid fibrils	1RVS		1 kDa/1	synthetic	-	MAS	Jaroniec et al. (2004)
Transthyretin (105-115) amyloid fibrils Protofilament, Doublet, Triplet and Quadruplet	2M5N 2M5K 2M5M 3ZPK	19062 19058 19060 19057	19 kDa/16 10 kDa/8 14 kDa/12 19 kDa/16	synthetic	-	MAS	Fitzpatrick et al. (2013)
Amyloid protofilaments of beta2-microglobulin fragment	2E8D	10202	10 kDa/4	Escherichia coli	-	MAS	Iwata et al. (2006)
WW domain of human amyloid CA 150	2NNT		18 kDa/4	Escherichia coli	-	MAS	Ferguson et al. (2006)
Beta-amyloid protein 40	2LMN 2LMO 2LMP 2LMQ 2M4J	18127 19009	52 kDa/12 78 kDa/18 39 kDa/9	synthetic human	-	MAS	Petkova et al. (2006) Paravastu et al. (2008) Lu et al. (2013)
Beta-amyloid protein 40 bearing the Osaka mutation	2MVX	25289	42 kDa/10	Escherichia coli	-	MAS	Schutz et al. (2014)
Amyloid fibrils of the HET-s (218-289) prion with small molecule Congo Red	2RNM 2KJ3 2LBU	11028 11064	43 kDa/5	Escherichia coli	-	MAS	Wasmer et al. (2008) Van Melckebeke et al. (2010) Schutz et al. (2011)
Fragment of the human islet amyloid polypeptide (hIAPP)	2KIB	20074	6 kDa/8	synthetic	-	MAS	Nielsen et al. (2009)
Type-III Secretion System Needle (from Salmonella typhimurium)	2LPZ	18276	257 kDa/29	Escherichia coli	-	MAS	Loquet et al. (2012)
Type-III Secretion System Needle - tetrameric building block (from Salmonella typhimurium)	2MEX	18276	35 kDa/4	Escherichia coli	-	MAS	Loquet et al. (2013)
Type-III Secretion System Needle (from Shigella flexneri)	2MME	18651	272 kDa/29	Escherichia coli	-	MAS and EM	Demers et al. (2014)
Capsid protein G8P of M13 bacteriophage	2MJZ	19747	184 kDa/35	Escherichia coli	-	MAS	Morag et al. (2015)

MEMBRANE PROTEINS IN MEMBRANES
Gramicidin	1MAG		4 kDa/2	synthetic	lipids	oriented	Ketchem et al. (1993)
AchR M2 channel	1CEK		3 kDa/1	Escherichia coli	lipids	oriented	Opella et al. (1999)
alpha-factor receptor M6	1PJD		2 kDa/1	synthetic	lipids	oriented	Valentine et al. (2001)
Influenza M2 channel residues 22-46	1NYJ		11 kDa/4	synthetic	lipids	oriented	Wang et al. (2001)
Influenza M2 channel residues 22-46 with amantadine	2H95		8 kDa/4	synthetic	lipids	oriented	Hu et al. (2007)
Influenza M2 channel residues 22-46 with amantadine	2KAD 2KQT	16020 16612	11 kDa/4	synthetic	lipids	MAS and oriented	Cady et al. (2009) Cady et al. (2010)
Influenza M2 channel residues 22-62	2L0J		20 kDa/4	Escherichia coli	lipids	oriented	Sharma et al. (2010)
fd coat protein	1MZT	5815	5 kDa/1	Escherichia coli	lipids	oriented	Marassi and Opella (2003)
HIV Vpu channel	1PJE 1PI7 1PI8		4 kDa/1	Escherichia coli	lipids	oriented	Park et al. (2003)
Stannin	1ZZA	6715	14 kDa/1	Escherichia coli	SDS	solution and oriented	Buck-Koehntop et al. (2005)
Integral membrane domain of the mercury transporter Mer F	2H3O 2LJ2	17914	6 kDa/1	Escherichia coli (C43)	bicelles DMPC	oriented bicelles MAS	De Angelis et al. (2006) Das et al (2012)
Full length mercury transporter Mer F	2M67 2MOZ	19115	9 kDa/1	Escherichia coli	bicelles and DMPC	oriented and MAS	Lu et al (2013) Tian et al (2014)
Protegrin-1	1ZY6		4 kDa/2	synthetic	POPC	MAS	Mani et al. (2006)
Mastoparan (membrane bound rather than transmembrane)	2CZP	10001	2 kDa	Escherichia coli	DPPC:DPPG=4:1	MAS	Todokoro et al. (2006)
human Phospholamban	2KB7 2KYV		30 kDa/5	Escherichia coli	DPC and lipids	solution, oriented and MAS	Traaseth et al. (2009) Verardi et al. (2011)
Pf1 coat protein	2KSJ	5877	5 kDa/1	Pseudomonas aeruginosa	DHPC, bicelles and lipids	solution and oriented	Park et al. (2010)
G-protein coupled chemokine receptor CXCR1	2LNL	18170	34 kDa/1	Escherichia coli	DMPC	MAS	Park et al. (2012)
N-terminal domain Htt17 of Huntingtin (membrane bound rather than transmembrane)	2LD2	17644	2 kDa/1	synthetic	POPC on glass plates and DPC micelles	oriented and solution	Michalek et al. (2013)
Rabbit cytochrome b5	2M33	18919	13 kDa/1	Escherichia coli	DPC and bicelles	solution and oriented	Ahuja et al. (2013)
Anabaena Sensory Rhodopsin	2M3G	18595	83 kDa/3	Escherichia coli	lipids (DMPC/DMPA:9/1)	MAS	Wang et al. (2013)
Salmonella Transmembrane Regulatory Peptide, MgtR	2MC7	19334	3 kDa/1	Synthetic	DMPC (37°C)	oriented	Jean-François et al. (2014)
Moronecidin	2MCU	19454	3 kDa/1	Synthetic	DMPC/DMPG bilayer (40°C)	oriented	Perrin et al. (2014)
Moronecidin	2MCV	19455	3 kDa/1	Synthetic	POPE/POPG bilayer (22°C)	oriented	Perrin et al. (2014)
Piscidin-3	2MCW	19456	2 kDa/1	Synthetic	DMPC/DMPG bilayer (40°C)	oriented	Perrin et al. (2014)
Piscidin-3	2MCX	19457	2 kDa/1	Synthetic	POPE/POPG bilayer (22°C)	oriented	Perrin et al. (2014)

MICRO-CRYSTALLINE MEMBRANE PROTEINS
human alpha-defensin HNP-1	2KHT	16254	3 kDa/1	Escherichia coli	microcrystalised outside the lipid membrane	MAS	Zhang et al. (2009)
Membrane protein complex DsbB-DsbA (with ubiquinone)	2LEG	17710	42 kDa/1	Escherichia coli (C43)	microcrystalised outside the lipid membrane with residual native lipids	MAS and X-ray	Tang et al. (2011)
DsbB (C41S mutant)	2LTQ	18493	18 kDa/1	Escherichia coli	microcrystalised outside the lipid membrane with residual native lipids	MAS and X-ray	Tang et al. (2013)
Membrane anchor domain of the trimeric autotransporter YadA	2LME	18108	34 kDa/3	Escherichia coli	microcrystalised outside the lipid membrane	MAS	Shahid et al. (2012)

OTHER PROTEINS
alpha-B crystallin	2KLR	16391	40 kDa/2	Escherichia coli	-	MAS	Jehle et al. (2010)
L,D-transpeptidase YkuD + peptidoglycan hexamuropeptide	2MTZ	25192	19 kDa/1 + 6 kDa/6	Escherichia coli + Bacillus subtilis	-	MAS	Schanda et al. (2014)

PROTEINS OF KNOWN STRUCTURE

DETERMINED BY SOLID-STATE NMR